The recommended daily allowance of vitamin B12 for adults isn’t much — 2.4 mcg, according to the NIH. More research is needed to make sound conclusions on the effect of vitamin B12 supplements on memory and cognitive function. The risk of developing any form of the condition was 34% lower, while it was 41% lower for more severe types (11). It also avoids miscarriage and premature birth. Accessed Aug. 23, 2017. Vitamin B-12 is also added to some foods and is available as an oral supplement. This article reviews 7 nutrients commonly lacking in…. Sardines are small, soft-boned saltwater fish. Two steps are required for the body to absorb vitamin B12 from food. It is one of eight B vitamins.It is a cofactor in DNA synthesis, and in both fatty acid and amino acid metabolism. Vitamin B-12 is necessary for several bodily processes, including nerve function and the production of DNA and red blood cells.. A person whose vitamin B-12 … B-Complex Vitamins: Benefits, Side Effects and Dosage, The Water-Soluble Vitamins: C and B Complex, Nutrition: Great Foods for Getting Vitamins A to K in Your Diet, Top 12 Foods That Are High in Vitamin B12, 9 Signs and Symptoms of Vitamin B12 Deficiency, 8 Common Signs You’re Deficient in Vitamins, 7 Nutrient Deficiencies That Are Incredibly Common, 7 Nutrients That You Can’t Get from Plants, People with gastrointestinal disorders, such as Crohn’s disease or celiac disease, Those who have had gastrointestinal surgeries, such as bariatric surgery or bowel resection surgery, Those who take metformin for blood sugar control, Those taking proton pump inhibitors for chronic heartburn. Facts & Comparisons eAnswers. In fact, one of the most common early signs of vitamin B12 deficiency is fatigue or lack of energy. High blood levels of the common amino acid homocysteine have been linked to an increased risk of heart disease. When taken at appropriate doses, vitamin B-12 supplements are generally considered safe. Vitamin D and vitamin B12 are two of the most potent vitamins “as defined by the amount of vitamin required to elicit a biological response” [5]. Taking a supplement may improve your energy level, but only if you’re deficient in this vitamin. Here are 9 health benefits of vitamin B12, all based on science. Further, knowing what vitamins are good for low platelet count help in diet and treatment plan, as appropriate. Another good way to assess one’s true B12 status is to measure total homocysteine (tHcy). Vitamin B12 does a lot of things for your body. However, this vitamin plays a vital role in synthesizing and metabolizing serotonin, a chemical responsible for regulating mood. Vitamin B12 deficiency in the beginning stages of pregnancy may increase the risk of birth defects, such as neural tube defects. The effect of vitamin B12 on mood is not yet fully understood. Uses of Vitamin B12-Folic Acid: It is used to help growth and good health. When you’re anemic, your body doesn’t have enough red blood cells to transport oxygen to your vital organs. The foods you eat play a big role in your overall health. But, when a person doesn’t have the vigor to do it, it could be due to the lack of B12. Low vitamin B12 levels cause a reduction in red blood cell formation and prevent them from developing properly (2). Vitamin B12 supplements have long been touted as the go-to product for a surge of energy. Studies have shown that vitamin B12 helps decrease homocysteine levels, which may reduce your risk of heart disease (20, 21, 22). Vitamin B12 supplements may help improve mood in people with an existing deficiency. Our general interest e-newsletter keeps you up to date on a wide variety of health topics. Vitamin B12 also helps prevent a type of anemia called megaloblastic anemia that makes people tired and weak. https://www.uptodate.com/contents/search. Vitamin B12 is involved in energy production in your body. This may help prevent the development of age-related macular degeneration. Methylcobalamin is the most active form of B12 in the body and is easily absorbed. Left untreated, a vitamin B-12 deficiency can lead to anemia, fatigue, muscle weakness, intestinal problems, nerve damage and mood disturbances. Vitamin B12 is required for proper red blood cell formation, neurological function, and DNA synthesis [ 1-5 ]. A diet lacking in nutrients may cause a variety of unpleasant symptoms. However, there is currently no scientific evidence to confirm that vitamin B12 supplements are effective in this regard (23). However, if you think that you might be at risk, speak to your doctor. It is involved in many vital processes in the body, including: Producing red blood cells Keeping the nervous system healthy Because your body is capable of storing several years' worth of vitamin B-12, deficiency is rare. Another study discovered that vitamin B12 deficiency was associated with twice the risk of severe depression (13). Healthy vitamin B12 levels are important for your hair, skin and nails. Maintaining adequate vitamin B12 levels may support your bone health. Though vitamin B12 supplements may help improve mood and depression in people with a deficiency, research does not currently suggest that they have the same effect in those with normal B12 levels. Micromedex 2.0 Healthcare Series. Vitamin B12 plays a vital role in helping your body produce red blood cells. Vitamin B12 is needed for the production of serotonin, a chemical responsible for regulating mood. Additionally, high vitamin B12 levels have been linked to better treatment outcomes and an increased probability of recovery from major depressive disorder (MDD) (14). 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